Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster

@article{Miquel1976EffectsOT,
  title={Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster
},
  author={Jaime Miquel and Paul R. Lundgren and Klaus G. Bensch and Henri Atlan},
  journal={Mechanisms of Ageing and Development},
  year={1976},
  volume={5},
  pages={347-370}
}
The effects of temperature on the aging process have been investigated in approximately 3500 imagoes of male Drosophila melanogaster (Oregon R), with focus on the following parameters: mortality, O2 utilization, vitality (as expressed by negative geotaxis and mating) and fine structural alterations in the abdominal organs and brain. The data on mortality kinetics of flies maintained continuously at 18 degrees, 21 degrees, 27 degrees or 30 degrees C or exposed in succession to 21 degrees and 27… Expand
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WITHIN-AND BETWEEN-GENERATION EFFECTS OF TEMPERATURE ON THE MORPHOLOGY AND PHYSIOLOGY OF DRO
-We investigated the effects of developmental and parental temperatures on several physiological and morphological traits of adult Drosophila melanogaster. Flies for the parental generation wereExpand
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References

SHOWING 1-10 OF 28 REFERENCES
Further studies on the thermally induced aging of Drosophila melanogaster.
TLDR
It was found that exposing Drosophila to ionizing radiation actually extends life expectancy, rather than shortens it, and it was shown that the reguiar replenishment of the housing and food of individuaiiy housed Dosophila produces a considerable extension of the life span. Expand
The effect of fluctuating environmental temperatures on the length of life of adult Drosophila.
TLDR
Adult Drosophila melanogaster aged in an environment in which the temperature fluctuated between 25°C and 30°C approximated to that expected according to the “rate of living” theory of ageing, though there was an indication that the daily exposure to the high temperature had a more than additive life-shortening effect. Expand
Effects of oxygen-nitrogen (1:1) at 760 torr on the life span and fine structure of drosophila melanogaster
TLDR
In the authors' opinion, oxygen poisoning of Drosophila may provide a valid model of accelerated aging, at least in regard to peroxidation injury of cell organelles and ceroid-lipofuscin accumulation. Expand
Independence of Temperature of the Rate of Ageing in Drosophila subobscura
TLDR
It is reported that the expectation that an animal which is kept for an appreciable part of its life-span at a high temperature and then transferred to a low temperature would be expected to die at a chronologically younger age than a similar animal kept continuously at the lower temperature is not realized. Expand
Natural aging and radiation-induced life shortening in Drosophila melanogaster.
TLDR
The view that irradiation results in life-shortening through a radiation syndrome mechanism which is essentially unrelated to aging is supported. Expand
Environmental Temperature and Life Span in Poikilotherms
TLDR
Drosophila subobscura experiments demonstrated that exposure of flies to a low temperature followed by their transfer to high temperatures at different ages reduced their initial expectation of life at the high temperatures by one day for every day spent at the low temperature. Expand
Temperature and length of life in Drosophila.
TLDR
The existence of a critical point in the temperature-length of life relationship indicates that the higher temperatures are life-shortening because they cause events which do not occur at the lower temperatures. Expand
Two Phases of Ageing in Drosophila Subobscura
TLDR
It was found that during the early part of the life span, over the range 15-30° C., every day spent at a low temperature reduced the expectation of life at a higher temperature by approximately 1 day, and little further change in this expectation occurred with increasing age at a lower temperature. Expand
Experimental Studies on the Duration of Life. XII. Influence of Temperature during the Larval Period and Adult Life on the Duration of the Life of the Imago of Drosophila melanogaster
TLDR
The origin of the present investigation was closely connected with a study of the influence of temperature on physical characteristics of Drosophila conducted by one of the authors, and the duration of life of flies genetically and phaenotypically identical is tested. Expand
Temperature and the rate of ageing in Drosophila subobscura
TLDR
Exposure to a lethal temperature in moist air for a time which just fails to kill adult flies causes a heat coma from which they can fully recover and can be repeated several times before the mortality rises appreciably, showing that if damage is done to the flies it is repairable. Expand
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