Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays.

@article{Lo2006EffectsOT,
  title={Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays.},
  author={Miranda C Y Lo and Dieter Bulach and David R. Powell and David A. Haake and James Matsunaga and Michael Paustian and Richard L. Zuerner and Ben Adler},
  journal={Infection and immunity},
  year={2006},
  volume={74 10},
  pages={5848-59}
}
Leptospirosis is an important zoonosis of worldwide distribution. Humans become infected via exposure to pathogenic Leptospira spp. from infected animals or contaminated water or soil. The availability of genome sequences for Leptospira interrogans, serovars Lai and Copenhageni, has opened up opportunities to examine global transcription profiles using microarray technology. Temperature is a key environmental factor known to affect leptospiral protein expression. Leptospira spp. can grow in… CONTINUE READING