Effects of technical parameters on the physicochemical properties of rifampicin-containing polylactide nanoparticles

Abstract

The aim of the present work was to assess the influences of the parameters of the process of preparing polylactide-based nanosomal medicinal formulations of rifampicin (Rif) on nanoparticle size, the level of Rif sorption, and the kinetics of Rif release in vitro. The most effective Rif sorption in nanoparticles (up to 90%) was obtained using polylactides… (More)
DOI: 10.1007/s11094-010-0420-y

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