Effects of tamoxifen therapy on lipid and lipoprotein levels in postmenopausal patients with node-negative breast cancer.

@article{Love1990EffectsOT,
  title={Effects of tamoxifen therapy on lipid and lipoprotein levels in postmenopausal patients with node-negative breast cancer.},
  author={Richard R. Love and Polly A Newcomb and Donald A. Wiebe and Tanya S. Surawicz and V. Craig Jordan and Paul P. Carbone and David DeMets},
  journal={Journal of the National Cancer Institute},
  year={1990},
  volume={82 16},
  pages={1327-32}
}
We conducted a 2-year, randomized, double-blind, placebo-controlled toxicity trial of therapy with tamoxifen (10 mg twice a day) in 140 postmenopausal women with a history of breast cancer and histologically negative axillary lymph nodes. These women had been treated with surgery with or without radiotherapy. At a 3-month evaluation, tamoxifen-treated women showed a significant decrease in fasting plasma levels of total cholesterol and low-density lipoprotein (LDL) cholesterol, which persisted… CONTINUE READING
72 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 72 extracted citations

Similar Papers

Loading similar papers…