Effects of tamoxifen on normal human dermal fibroblasts.


OBJECTIVE To evaluate the effects of tamoxifen on the growth and autocrine growth factor production of human dermal fibroblasts from the face. METHODS In vitro study of normal adult dermal fibroblast cells developed from surgical specimens in a serum-free model. Cell cultures were exposed to 5-, 8-, 12-, 16-, and 50-microg/mL concentrations of tamoxifen… (More)


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