Effects of systemic inhibition of neuronal nitric oxide synthase in diabetic rats.

@article{Komers2000EffectsOS,
  title={Effects of systemic inhibition of neuronal nitric oxide synthase in diabetic rats.},
  author={Radko Komers and Terry T. Oyama and Justin G Chapman and K Allison and Sonya Anderson},
  journal={Hypertension},
  year={2000},
  volume={35 2},
  pages={655-61}
}
Diabetes is associated with alterations in nitric oxide-mediated vasomotor function. The role of nitric oxide generated via the neuronal nitric oxide synthase pathway in the control of systemic and renal hemodynamics in diabetes has not been studied. To explore the hypothesis that diabetic vascular dysfunction is in part caused by altered neuronal nitric oxide synthase activity, systemic and renal hemodynamics were assessed before and after acute inhibition of this enzyme with a specific… CONTINUE READING