Effects of systemic indomethacin, meclizine, and BW755C on chronic ultraviolet B-induced effects in hairless mouse skin.

@article{Kochevar1993EffectsOS,
  title={Effects of systemic indomethacin, meclizine, and BW755C on chronic ultraviolet B-induced effects in hairless mouse skin.},
  author={Irene E Kochevar and Michael Moran and Nicholas Lyon and Thomas Flotte and E Siebert and Richard W. Gange},
  journal={The Journal of investigative dermatology},
  year={1993},
  volume={100 2},
  pages={
          186-93
        }
}
Chronic exposure of hairless mice to ultraviolet B (UVB) radiation is associated with inflammation as well as an altered macromolecular composition of the dermis. This study was designed to determine whether or not various systemic anti-inflammatory agents inhibit chronic UVB-induced changes in the macromolecular content of the dermis and, if so, whether each agent had the same or different effects. The agents and doses were chosen for their ability to inhibit the changes induced by a single… Expand
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