Effects of synthetic colloid and crystalloid solutions on hemorheology in vitro and in hemorrhagic shock

@inproceedings{Chen2015EffectsOS,
  title={Effects of synthetic colloid and crystalloid solutions on hemorheology in vitro and in hemorrhagic shock},
  author={Gan Chen and Jingxiang Zhao and Penglong Li and Xuemei Kan and Guoxing You and Ying Wang and Yujing Yin and Xin Robert Luo and Yuhua Zhang and Lian Zhao and Hong Zhou},
  booktitle={European Journal of Medical Research},
  year={2015}
}
BackgroundPlasma expanders are commonly used in the management of critically ill patients, which may exhibit altered hemorheology. We evaluated the effects of various synthetic colloids and Lactated Ringer’s (LR) solution on hemorheological parameters in vitro and in a rodent hemorrhagic shock model.MethodsFor the in vitro experiments, rat blood was incubated with hydroxyethyl starch (HES) 130/0.4, HES 200/0.5, succinylated gelatine (GEL), or LR at various ratios. The control consisted of blood… CONTINUE READING

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