Effects of sympathetic nerve blockade on vasoconstrictive properties of nitric oxide synthase inhibition in sheep.

@article{Booke1997EffectsOS,
  title={Effects of sympathetic nerve blockade on vasoconstrictive properties of nitric oxide synthase inhibition in sheep.},
  author={Michael Booke and Ren{\'e} Waurick and h c Hugo Van Aken and H. G. Bone and Achim Meissner and Thomas Prien and Joerg Meyer},
  journal={Cardiovascular research},
  year={1997},
  volume={36 1},
  pages={111-7}
}
OBJECTIVE Inhibition of nitric oxide synthase causes intense vasoconstriction. This effect is thought to be dependent on sympathetic nerve activity. Thus, we investigated the vasoconstrictive effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in sheep, in which a reversible sympathetic block was established by thoracic… CONTINUE READING