Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model.

@article{Isayeva2007EffectsOS,
  title={Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model.},
  author={Tatyana Isayeva and Diptiman Chanda and Lisa Kallman and Isam Eldin Eltoum and Selvarangan Ponnazhagan},
  journal={Cancer research},
  year={2007},
  volume={67 12},
  pages={5789-97}
}
Antiangiogenic therapy is a promising alternative for prostate cancer growth and metastasis and holds great promise as an adjuvant therapy. The present study evaluated the potential of stable expression of angiostatin and endostatin before the onset of neoplasia and during the early and late stages of prostate cancer progression in transgenic adenocarcinoma of mouse prostate (TRAMP) mice. Groups of 5-, 10-, and 18-week-old male TRAMP mice received recombinant adeno-associated virus-6 encoding… CONTINUE READING

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