Effects of surgical hypophysectomy in a man with malignant melanoma.

  title={Effects of surgical hypophysectomy in a man with malignant melanoma.},
  author={Michael B. Shimkin and Edwin B. Boldrey and Keith H. Kelly and Howard R. Bierman and P. Ortega and Howard C. Naffziger},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={12 4},
MALIGNANT melanoma in man displays a number of features which suggest that its development and growth may be related to or influenced by the endocrine system. Melanomas are almost never malignant before puberty, are not observed in castrated individuals, and their growth and dissemination are markedly accelerated during puberty and during pregnancy (1, 2). The clinical course of melanoma with metastases is uncompromising in its inexorable progress and cannot be modified by any presently known… CONTINUE READING

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