Effects of supplemental erythropoietin on its receptor expression and signal transduction pathways in rat model of retinal detachment.

PURPOSE The aim of this study was to investigate the effects of supplemental erythropoietin (EPO) on its receptor (EPOR) and signal transduction pathways in rat model of retinal detachment (RD). METHODS To investigate the effect of EPO on EPOR expression in RD rats 100, 200 or 400 ng EPO was injected into the vitreous cavity immediately after RD model was… CONTINUE READING