Effects of superior mesenteric artery stenosis on splanchnic and systemic hemodynamics in conscious rats with biliary cirrhosis.

BACKGROUND/AIMS Since portal tributary blood flow is increased in portal hypertension due to cirrhosis, a reduction in mesenteric arterial blood flow should decrease portal pressure. METHODS Calibrated stenosis of the superior mesenteric artery was performed in bile duct ligated rats, using a 22-gauge needle. Arterial stenosis was performed 4 weeks after… CONTINUE READING