Effects of sulfhydryl and other reagents on the diffusional permeability of dog erythrocytes to small solutes.

@article{Garrick1983EffectsOS,
  title={Effects of sulfhydryl and other reagents on the diffusional permeability of dog erythrocytes to small solutes.},
  author={Rita Anne Garrick and Bhupendra C K Patel and Francis P. Chinard},
  journal={Biochimica et biophysica acta},
  year={1983},
  volume={734 1},
  pages={
          105-13
        }
}
The effects of p-chloromercuriphenylsulfonic acid (PCMBS), 5,5'-dithiobis (2-nitrobenzoic acid) (DTNB), phloretin and thiourea on the diffusional permeability of dog erythrocytes to tritiated water and to small 14C-labeled lipophilic and hydrophilic solutes were measured at 37 degrees C by means of the linear diffusion technique. Permeability to 3HHO was significantly decreased by PCMBS but was not affected by the other reagents. The permeability to the small hydrophilic solutes acetamide and… CONTINUE READING
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