Effects of sucrose ester structures on liposome-mediated gene delivery.

@article{Zhao2018EffectsOS,
  title={Effects of sucrose ester structures on liposome-mediated gene delivery.},
  author={Yinan Zhao and An Liu and Yanyan Du and Yingnan Cao and Enxia Zhang and Quan Zhou and Hua Hai and Yuhong Zhen and Shubiao Zhang},
  journal={Acta biomaterialia},
  year={2018},
  volume={72},
  pages={
          278-286
        }
}
Sucrose esters (SEs) have great potential applications in gene delivery because of their low toxicity, excellent biocompatibility, and biodegradability. By using tripeptide-based lipid (CDO) as a model lipid and SEs as helper lipids, a series of liposomes were prepared. The SEs with hydrophilic-lipophilic balance (HLB) values of 1, 6, 11, or 16 and the fatty acids of laurate, stearate, or oleate were used in the liposomes. We investigated the effect of HLB values of SEs and fatty acid types on… CONTINUE READING

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