Effects of substance P on mesenteric lymphatic contractility in the rat.

@article{Amerini2004EffectsOS,
  title={Effects of substance P on mesenteric lymphatic contractility in the rat.},
  author={Sandra Amerini and Marina Ziche and Steven T Greiner and David C Zawieja},
  journal={Lymphatic research and biology},
  year={2004},
  volume={2 1},
  pages={2-10}
}
BACKGROUND Substance P (SP) is associated with lymphatic tissue and is a putative mediator of inflammation. The lymph pump is one of the major "safety factors" preventing edema and its activity is altered by inflammatory mediators. The impact of SP on lymphatics was studied in the rat mesentery. METHODS AND RESULTS Rats were prepared for in situ lymphatic observation using intravital videomicroscopic techniques. Sections of the small intestine and mesentery were exteriorized and superfused… CONTINUE READING