Effects of subacute treatment with benzopyranopyrimidines in hemostasis and experimental thrombosis in mice.

@article{Ballabeni2004EffectsOS,
  title={Effects of subacute treatment with benzopyranopyrimidines in hemostasis and experimental thrombosis in mice.},
  author={Vigilio Ballabeni and Francesco Calcina and Massimiliano Tognolini and Olga Bruno and Cesare Manotti and Elisabetta Barocelli},
  journal={Life sciences},
  year={2004},
  volume={74 15},
  pages={
          1851-9
        }
}
  • Vigilio Ballabeni, Francesco Calcina, +3 authors Elisabetta Barocelli
  • Published in Life sciences 2004
  • Biology, Medicine
  • The antithrombotic activity of a series of benzopyranopyrimidine derivatives was investigated in platelet-dependent and independent pulmonary thromboembolism in mice. Intraperitoneal subacute treatment with 2-morpholino derivative 3c significantly prevented paralysis due to collagen plus epinephrine-induced pulmonary thrombosis while 2-piperidino substituted derivative 3h significantly protected mice from paralysis caused by thrombin-induced intravascular fibrin formation at dosage not… CONTINUE READING

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