Effects of strontium-doped bioactive glass on the differentiation of cultured osteogenic cells.

@article{Isaac2011EffectsOS,
  title={Effects of strontium-doped bioactive glass on the differentiation of cultured osteogenic cells.},
  author={Juliane Isaac and Joe Nohra and Jianmin Lao and Edouard Jallot and J. M. Nedelec and Ariane Berdal and Jean Michel Sautier},
  journal={European cells & materials},
  year={2011},
  volume={21},
  pages={130-43}
}
There is accumulating evidence that strontium-containing biomaterials have positive effects on bone tissue repair. We investigated the in vitro effect of a new Sr-doped bioactive glass manufactured by the sol-gel method on osteoblast viability and differentiation. Osteoblasts isolated from foetal mouse calvaria were cultured in the presence of bioactive glass particles; particles were undoped (B75) or Sr-doped with 1 wt.% (B75-Sr1) and 5 wt.% (B75-Sr5). Morphological analysis was carried out by… CONTINUE READING