Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children.

@article{Araya2009EffectsOS,
  title={Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children.},
  author={Rodolfo Araya and Xianzhang Hu and Jon Heron and Mary-Anne Enoch and Jonathan Evans and Glyn Lewis and David Walter Nutt and David Goldman},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2009},
  volume={150B 5},
  pages={
          670-82
        }
}
There has been a large but inconsistent literature on interactions between the 5-HTTLPR polymorphism of the serotonin transporter gene and adversity on emotional disorders. We investigated these interactions in 4,334 children from a birth longitudinal cohort: the Avon Longitudinal Study of Parents and Children (ALSPAC). We measured emotional symptoms at 7 years with the Strengths and Difficulties Questionnaire. Mothers rated stressful life events between ages 5 and 7 years. Maternal depression… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 31 CITATIONS

Prenatal and Postnatal Maternal Mental Health and School-Age Child Development: A Systematic Review

  • Maternal and Child Health Journal
  • 2013
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The role of peer rejection in adolescent depression.

VIEW 6 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED