Effects of storage duration and volume on the quality of leukoreduced apheresis-derived platelets: implications for pediatric transfusion medicine.

@article{Winkler2010EffectsOS,
  title={Effects of storage duration and volume on the quality of leukoreduced apheresis-derived platelets: implications for pediatric transfusion medicine.},
  author={Anne M. Winkler and Chelsea A Sheppard and Elizabeth E Culler and Robert Gruber Barbara Liskov Andrew C. Myers and Alexander Duncan and Marta-In{\'e}s Castillejo and Christopher D. Hillyer and Cassandra D Josephson},
  journal={Transfusion},
  year={2010},
  volume={50 10},
  pages={2193-8}
}
BACKGROUND Platelet (PLT) storage adversely affects PLT structure and function in vitro and is associated with decreased PLT recovery and function in vivo. In pediatric transfusion medicine, it is not uncommon for small residual volumes to remain in parent units after aliquot preparation of leukoreduced apheresis-derived PLTs (LR-ADP). However, limited data exist regarding the impact of storage on residual small-volume LR-ADP. STUDY DESIGN AND METHODS Standard metabolic testing was performed… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 24 references

In vitro evaluation of metabolic changes and residual platelet responsiveness in photochemical treated and gamma - irradiated single - donor platelet concentrates during long - term storage

  • G DiMinno, MJ Silver, S Murphy
  • 2007

Aggrego - metry detects platelet hyperreactivity in healthy individu

  • PF vanderMeer, H Vrielink, RN Pietersz
  • Blood
  • 2005

Efficacy of platelet pheresis utilization with small volume

  • K Nicol, T Hudson, P Moder
  • TRANSFUSIONS
  • 2004

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