Effects of stimulation or inhibition of lipid peroxidation on freezing-thawing of mouse embryos.

@article{Tarn1993EffectsOS,
  title={Effects of stimulation or inhibition of lipid peroxidation on freezing-thawing of mouse embryos.},
  author={Juan Jos{\'e} Tar{\'i}n and Alan O. Trounson},
  journal={Biology of reproduction},
  year={1993},
  volume={49 6},
  pages={1362-8}
}
This study was conducted to determine whether the tolerance of embryos to the stress of freezing and thawing can be modified by including in the incubation medium stimulators or inhibitors of membrane lipid peroxidation. Mouse zygotes were cultured in medium M16, supplemented or not with FeSO4, apotransferrin, and/or ascorbate. In each culture supplement, 8-cell embryos were randomly allocated to an untreated (nonfrozen) control group, or treatment by freezing using slow or ultra-rapid cooling… CONTINUE READING

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