Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women

@article{Goss2006EffectsOS,
  title={Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women},
  author={Paul E Goss and Peyman Hadji and Milayna Subar and Paula Pinheiro de Abreu and Torben Thomsen and Jos{\'e} Bank{\'e}-Bochita},
  journal={Breast cancer research : BCR},
  year={2006},
  volume={9},
  pages={R52 - R52}
}
In contrast to nonsteroidal aromatase inhibitors, the steroidal aromatase inactivator exemestane does not have detrimental effects on bone in animal models. This study was designed to compare the effects of exemestane with the nonsteroidal aromatase inhibitors anastrozole and letrozole on serum and urine levels of biomarkers of bone turnover in healthy postmenopausal women. Changes in the concentrations of bone-turnover markers, estrogens, and lipids were assessed after daily administration of… CONTINUE READING