Effects of steroid hormones and peptide growth factors on protooncogene c-fos expression in human breast cancer cells.

@article{Wilding1988EffectsOS,
  title={Effects of steroid hormones and peptide growth factors on protooncogene c-fos expression in human breast cancer cells.},
  author={George Wilding and Marc E. Lippman and Edward P. Gelmann},
  journal={Cancer research},
  year={1988},
  volume={48 4},
  pages={802-5}
}
To investigate if the estrogen control of the tumorigenic phenotype of breast cancer cells was mediated through activation of the c-fos protooncogene, we examined the expression of this oncogene in MCF-7 cells. In cells synchronized by double thymidine blockade, the peptide growth factors transforming growth factor alpha and epidermal growth factor… CONTINUE READING