Effects of stent sizing on endothelial and vessel wall stress: potential mechanisms for in-stent restenosis.

@article{Chen2009EffectsOS,
  title={Effects of stent sizing on endothelial and vessel wall stress: potential mechanisms for in-stent restenosis.},
  author={Henry Y. Chen and James J Hermiller and Anjan Kumar Sinha and Michael S Sturek and Luoding Zhu and Ghassan S. Kassab},
  journal={Journal of applied physiology},
  year={2009},
  volume={106 5},
  pages={1686-91}
}
Stent sizing and apposition have been shown to be important determinants of clinical outcome. This study evaluates the mechanical effects of undersizing and oversizing of stents on endothelial wall shear stress (WSS) and vessel wall stress to determine a possible biomechanical mechanism of in-stent restenosis and thrombosis. Three-dimensional computational models of stents, artery, and internal fluid were created in a computer-assisted design package, meshed, and solved in finite element and… CONTINUE READING