Effects of some tricyclic psychopharmacons and structurally related compounds on motility ofProteus vulgaris

@article{Molnr2004EffectsOS,
  title={Effects of some tricyclic psychopharmacons and structurally related compounds on motility ofProteus vulgaris},
  author={J{\'a}nos Moln{\'a}r and Jie Ren and Jette Elisabeth Kristiansen and Masahiro Nakamura},
  journal={Antonie van Leeuwenhoek},
  year={2004},
  volume={62},
  pages={315-320}
}
A simple test for the evaluation of drugs interfering with bacterial motility was established withProteus vulgaris. With this model, promethazine, 7-hydroxy-chlorpromazine, imipramine, 7,8-dioxochlorpromazine and acridine orange were shown to exert significant motility and swarming inhibitory action onProteus vulgaris strains at subinhibitory concentrations. Quinidine enhanced the antimotility effect of promethazine. The antimotility effect of promethazine was synergized by proton pump… 

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