Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities

@article{Battistin2004EffectsOS,
  title={Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities},
  author={L. Battistin and M. Varotto and Giorgio Berlese and G. Roman},
  journal={Neurochemical Research},
  year={2004},
  volume={9},
  pages={225-231}
}
The effect of anticonvulsant drugs was examined on brain GABA levels and GAD and GABA-T activities. The level of GABA was increased by the treatment with diphenylhydantoin. The drug had no effect on GABA-T activity, whereas GAD activity was inhibited. Carbamazepine increased the GABA level but did not effect GAD and GABA-T activities. Diazepam had no effect on GABA level and GAD activity, whereas it caused a slight inhibition of GABA-T activity. Phenobarbital administration decreased GABA level… Expand
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