Effects of somatostatin on the external secretion of the pancreas of the rat.

@article{Chariot1978EffectsOS,
  title={Effects of somatostatin on the external secretion of the pancreas of the rat.},
  author={Jacques Chariot and Claude Roz{\'e} and Claude Vaille and C J Debray},
  journal={Gastroenterology},
  year={1978},
  volume={75 5},
  pages={832-7}
}
The effects of somatostatin on the secretions of the exocrine pancreas were studied in anesthetized and conscious fistula rats. Somatostatin resulted in a dose-dependent decrease of basal secretion (flow, bicarbonate, protein) in conscious rats. In anesthetized rats, basal secretion was initially augmented by bolus injections of 10 to 50 microgram per kg and was subsequently decreased by venous infusions of somatostatin at 1.5 to 100 microgram.kg-1.hr-1. This inhibition, which was poorly dose… CONTINUE READING

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