Effects of somatostatin and verapamil on growth hormone release and 45Ca fluxes.

@article{Schofield1978EffectsOS,
  title={Effects of somatostatin and verapamil on growth hormone release and 45Ca fluxes.},
  author={Julian Schofield and Robert Bicknell},
  journal={Molecular and cellular endocrinology},
  year={1978},
  volume={9 3},
  pages={255-68}
}
Increasing the extracellular K+ concentration to 71 mM causes a phasic release of growth hormone and efflux of 45Ca from perifused bovine pituitary cells. Verapamil (20 micron) partially inhibits the initial phase of growth hormone release and 45Ca efflux and completely inhibits the second phase. Somatostatin (1 microgram/ml) partially inhibits both phases… CONTINUE READING