Effects of soft interactions and bound mobility on diffusion in crowded environments: a model of sticky and slippery obstacles.

@article{Stefferson2017EffectsOS,
  title={Effects of soft interactions and bound mobility on diffusion in crowded environments: a model of sticky and slippery obstacles.},
  author={Michael W. Stefferson and Samantha Norris and Franck J Vernerey and M. D. Betterton and Loren E Hough},
  journal={Physical biology},
  year={2017},
  volume={14 4},
  pages={
          045008
        }
}
Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies the kinetics and equilibrium behavior of tracers. While previous theoretical studies of particle diffusion have typically assumed either impenetrable obstacles or binding interactions that immobilize the particle, in many cellular contexts bound particles remain mobile. Examples include membrane proteins or lipids… CONTINUE READING
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