Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study.

@article{Anthonisen1994EffectsOS,
  title={Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study.},
  author={Nicholas R. Anthonisen and John E. Connett and James P. Kiley and Murray D. Altose and William C. Bailey and A. Sonia Buist and William A Conway and Paul L. Enright and Richard E. Kanner and Peggy O'Hara},
  journal={JAMA},
  year={1994},
  volume={272 19},
  pages={1497-505}
}
OBJECTIVE To determine whether a program incorporating smoking intervention and use of an inhaled bronchodilator can slow the rate of decline in forced expiratory volume in 1 second (FEV1) in smokers aged 35 to 60 years who have mild obstructive pulmonary disease. DESIGN Randomized clinical trial. Participants randomized with equal probability to one of the following groups: (1) smoking intervention plus bronchodilator, (2) smoking intervention plus placebo, or (3) no intervention. SETTING… CONTINUE READING
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