Effects of slowed gastrointestinal motility on levodopa pharmacokinetics.

Abstract

Autonomic disorders are often seen in Parkinson's disease, with disturbances of the gastrointestinal tract occurring most frequently. These disorders, mainly a delay in gastric emptying and slowed gastrointestinal motility, can modify the pharmacokinetics and effectiveness of drugs used to treat Parkinson's disease and administered orally. In this study, we… (More)
DOI: 10.1016/j.autneu.2010.03.016

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