Effects of sleep-disordered breathing on cerebrovascular regulation: A population-based study.

@article{Morgan2010EffectsOS,
  title={Effects of sleep-disordered breathing on cerebrovascular regulation: A population-based study.},
  author={Barbara J Morgan and Kevin J Reichmuth and Paul E. Peppard and Laurel Finn and Steven R Barczi and Terry Young and F. Javier J Nieto},
  journal={American journal of respiratory and critical care medicine},
  year={2010},
  volume={182 11},
  pages={1445-52}
}
RATIONALE Cerebrovascular regulation is impaired in patients with moderate to severe obstructive sleep apnea; however, it is unknown whether this impairment exists in individuals with less severe sleep-disordered breathing. OBJECTIVES To test the hypothesis that cerebrovascular responses to hypercapnia are attenuated in a nonclinical population-based cohort. METHODS A rebreathing test that raised end-tidal CO₂ tension by 10 mm Hg was performed during wakefulness in 373 participants of the… CONTINUE READING
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