Effects of sleep and sleep loss on immunity and cytokines.

@article{Irwin2002EffectsOS,
  title={Effects of sleep and sleep loss on immunity and cytokines.},
  author={Michael R. Irwin},
  journal={Brain, behavior, and immunity},
  year={2002},
  volume={16 5},
  pages={503-12}
}
Sleep is hypothesized to be a restorative process that is important for the proper functioning of the immune system. Severity of disordered sleep in depressed- and alcoholic subjects correlates with declines in natural- and cellular immunity and is associated with alterations in the complex cytokine network. Sleep loss has a role in mediating these immune changes as experimentally induced partial night sleep deprivation replicates the kind of sleep loss found in clinical samples and induces a… CONTINUE READING
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Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men

  • E. Sp€ath-Schwalbe, K. Hansen, +5 authors J. Born
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