Effects of sleep and sleep loss on immunity and cytokines.

  title={Effects of sleep and sleep loss on immunity and cytokines.},
  author={Michael R. Irwin},
  journal={Brain, behavior, and immunity},
  volume={16 5},
Sleep is hypothesized to be a restorative process that is important for the proper functioning of the immune system. Severity of disordered sleep in depressed- and alcoholic subjects correlates with declines in natural- and cellular immunity and is associated with alterations in the complex cytokine network. Sleep loss has a role in mediating these immune changes as experimentally induced partial night sleep deprivation replicates the kind of sleep loss found in clinical samples and induces a… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
86 Citations
56 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 86 extracted citations


Publications referenced by this paper.
Showing 1-10 of 56 references

Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men

  • E. Sp€ath-Schwalbe, K. Hansen, +5 authors J. Born
  • J. Clin
  • 1998
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…