Effects of single and combined chemotherapeutic agents on hemopoietic stem cells in mice

@article{Jenkins1976EffectsOS,
  title={Effects of single and combined chemotherapeutic agents on hemopoietic stem cells in mice},
  author={Vernon K. Jenkins and John J. Costanzi and H N Ellis},
  journal={American Journal of Hematology},
  year={1976},
  volume={1}
}
Bone marrow cell responses to injections of nitrogen mustard, oncovin, procarbazine, hydrocortisone, and a regimen of all four drugs (MOPH) were evaluated in CRF1 and C57B 1/6 mice by determining bone marrow cellularity and content of transplantable colony forming units (CFU) after treatment. The study was done to determine whether the combined regimen, which is widely used clinically in treatment of disseminated Hodgkin's disease, is more or less detrimental to the hemopoietic system than the… Expand
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