Effects of sildenafil citrate on hepatic function and regeneration in normal and alcohol-fed rats.

@article{Ji2005EffectsOS,
  title={Effects of sildenafil citrate on hepatic function and regeneration in normal and alcohol-fed rats.},
  author={Hong Ji and Hong Shen and Julia Uhanova and Manna Zhang and Gerald Y Minuk and Yuewen Gong},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2005},
  volume={25 4},
  pages={913-9}
}
Sildenafil citrate is a potent inhibitor of specific phosphodiesterase-5, which mediates metabolism of intracellular second message -- cGMP. Sildenafil citrate has been widely used for erectile dysfunction in men. Moreover, it is known that men with liver diseases have higher rate of erectile dysfunction. Furthermore, it has been demonstrated that nitric… CONTINUE READING