Effects of short-course androgen therapy on the neurodevelopmental profile of infants and children with 49,XXXXY syndrome.

@article{SamangoSprouse2011EffectsOS,
  title={Effects of short-course androgen therapy on the neurodevelopmental profile of infants and children with 49,XXXXY syndrome.},
  author={Carole Samango-Sprouse and Andrea Gropman and Teresa Sadeghin and Madison Kingery and Margaret Lutz-Armstrong and Alan D Rogol},
  journal={Acta paediatrica},
  year={2011},
  volume={100 6},
  pages={
          861-5
        }
}
AIM The aim of this investigation was to ascertain whether an early course of androgen treatment (three injections testosterone enanthate, 25 mg) could have a positive impact on any domains of neurodevelopmental function in boys with 49,XXXXY. METHODS A total of 22 boys with a karyotype of 49,XXXXY participated in a multidisciplinary assessment of neurocognition, speech and language, paediatric neurology and endocrinology evaluations. One group had received early androgen and another group… CONTINUE READING
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