Effects of short‐term cinnamon ingestion on in vivo glucose tolerance

  title={Effects of short‐term cinnamon ingestion on in vivo glucose tolerance},
  author={Thomas P. J. Solomon and Andrew K. Blannin},
Aims:  Various spices display insulin‐potentiating activity in vitro, and in particular, cinnamon spice and its phenolic extracts have been shown to exhibit these capabilities. In vivo study shows that cinnamon may have beneficial effects on glucose homeostasis; therefore the aim of this study was to further investigate this phenomenon in humans. 
The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance
The aim of this review was to examine the results of randomized controlled clinical trials of cinnamon and evaluate the therapeutic potential amongst patients with diabetes and insulin‐resistant patients, particularly the ability to reduce blood glucose levels and inhibit protein glycation.
Health benefits of cinnamon supplement, in vitro and in vivo
Cinnamomum cassia supplementation produced important health benefits in vitro and in vivo, therefore it may be useful as a natural herbal remedy for obesity and CVD.
Cinnamon and Health
The use of cinnamon as an adjunct to the treatment of type 2 diabetes mellitus is the most promising area, but further research is needed before definitive recommendations can be made.
Effects of Cinnamon on Blood Glucose among Type 1 and Type 2 Diabetic Individuals: A Comparative Study
These data support the efficacy of cinnamon on reducing FBG in type 1 and type 2 diabetes and suggest that this naturally-occurring spice can reduce risk factors associated with diabetes.
Effect of Cinnamon Tea on Postprandial Glucose Concentration
Evidence is provided that cinnamon tea, obtained from C. burmannii, could be beneficial for controlling glucose metabolism in nondiabetic adults during postprandial period.
Effects of acute intake of grape/pomegranate pomace dietary supplement on glucose metabolism and oxidative stress in adults with abdominal obesity
It is suggested that a single realistic dose of grape/pomegranate pomace is not able to clearly improve glucose metabolism; chronic intake remains to be evaluated.
Acute Effects of Cinnamon Spice on Post-prandial Glucose and Insulin in Normal Weight and Overweight/Obese Subjects: A Pilot Study
Cinnamon consumption differentially affected post-prandial hormonal responses in normal and overweight/obese participants, with a significant reduction of one of the primary outcomes post- prandial insulin response.
Dietary spices in health and diseases (II).
  • K. Kochhar
  • Medicine
    Indian journal of physiology and pharmacology
  • 2008
This essay attempts to adjudicate the traditional use of dietary spices based on factual research evidence for their multivalent actions as health promoting dietary additives as well as putative therapeutic agents.
Effect of cassia cinnamon intake on improvement of the glycemic response: An updated meta-analysis: Focus on preparation of dehydrated powder and water extract
'계피' 건조분말의 경우 하루 1~6 g씩 섭취하였을 공복혈당은 -1.55 mmol/L...


Effects of a cinnamon extract on plasma glucose, HbA1c, and serum lipids in diabetes mellitus type 2
The aim of this trial was to determine whether an aqueous cinnamon purified extract improves glycated haemoglobin A1c, fasting plasma glucose, total cholesterol, low‐density lipoprotein (LDL), high‐density lipid (HDL) and triacylglycerol concentrations in patients with type 2 diabetes.
Cinnamon extract prevents the insulin resistance induced by a high-fructose diet.
The results suggest that early CE administration to HFD-fed rats would prevent the development of insulin resistance at least in part by enhancing insulin signaling and possibly via the NO pathway in skeletal muscle.
Whole Cinnamon and Aqueous Extracts Ameliorate Sucrose-Induced Blood Pressure Elevations in Spontaneously Hypertensive Rats
Cinnamon is used for flavor and taste in food preparation, but cinnamon may have additional roles in glucose metabolism and BP regulation, therefore, BP regulation may not only be influenced favorably by limiting the amounts of dietary substances that have negative effects on BP and insulin function but also by the addition of beneficial ones that have positive effects.
Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients.
Cinnamon supplementation (1.5 g/d) does not improve whole-body insulin sensitivity or oral glucose tolerance and does not modulate blood lipid profile in postmenopausal patients with type 2 diabetes.
Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro.
The positive effects of specific plant extracts on insulin activity suggest a possible role of these plants in improving glucose and insulin metabolism.
Insulin potentiating factor and chromium content of selected foods and spices
An unidentified factor that potentiates the action of insulin in glucose metabolism was investigated in selected foods and spices, and cinnamon, cloves, bay leaves, and turmeric potentiated insulin activity more than three-fold.
Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity.
Water-soluble polyphenol polymers from cinnamon that increase insulin-dependent in vitro glucose metabolism roughly 20-fold and display antioxidant activity were isolated and characterized by nuclear magnetic resonance and mass spectroscopy.
Decelerating gastric emptying: therapeutic possibilities in type 2 diabetes.
Clinical manipulation of gastric emptying rates may have therapeutic potential in glycaemic control and agents such as POT II may have a therapeutic indication in patients with recently diagnosed Type 2 diabetes.