Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.

@article{Costi2014EffectsOS,
  title={Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.},
  author={D. Costi and A. Cyna and Samira Ahmed and K. Stephens and P. Strickland and J. Ellwood and Jessica N Larsson and C. Chooi and L. Burgoyne and P. Middleton},
  journal={The Cochrane database of systematic reviews},
  year={2014},
  volume={9},
  pages={
          CD007084
        }
}
BACKGROUND Sevoflurane is an inhaled volatile anaesthetic that is widely used in paediatric anaesthetic practice. Since its introduction, postoperative behavioural disturbance known as emergence agitation (EA) or emergence delirium (ED) has been recognized as a problem that may occur during recovery from sevoflurane anaesthesia. For the purpose of this systematic review, EA has been used to describe this clinical entity. A child with EA may be restless, may cause self-injury or may disrupt the… Expand

Paper Mentions

Interventional Clinical Trial
Emergence delirium (ED) infers the occurrence of behavior and cognition changes during the early postoperative period. Main signs and symptoms of ED are the disturbances of… Expand
ConditionsDNA Methylation, Emergence Delirium, Postoperative Complications
InterventionDrug
Interventional Clinical Trial
Emergence agitation (EA) is a dissociated state of consciousness in which the child is inconsolable, irritable, uncooperative, typically thrashing, crying, moaning, or incoherent… Expand
ConditionsEmergence Agitation
InterventionDrug
Interventional Clinical Trial
The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of… Expand
ConditionsDelirium
InterventionOther
[Emergence delirium in children - prophylaxis and treatment].
TLDR
A child-focused approach to reduce preoperative anxiety focusing on distraction methods rather than pharmacological sedation may be the key as well as sufficient postoperative pain control and the use of total intravenous anesthesia. Expand
Intraoperative clonidine for prevention of postoperative agitation in children anaesthetised with sevoflurane (PREVENT AGITATION): a randomised, placebo-controlled, double-blind trial.
TLDR
On the basis of the results, clonidine might be used to safely prevent postoperative agitation in boys anaesthetised with sevoflurane and the observed effect was not significant in girls. Expand
Emergence agitation in children: risk factors, prevention, and treatment
TLDR
Perioperative administration of opioids, midazolam, ketamine, alpha-2 agonist sedatives, and nonsteroidal anti-inflammatory drugs has demonstrated efficacy in the prevention and treatment of EA. Expand
Emergence Delirium in Perioperative Pediatric Care: A Review of Current Evidence and New Directions
TLDR
A comprehensive review of anesthetic considerations for pediatric ED is provided and an update on techniques that have been found to be effective in reducing the overall risk of developing postoperative ED in pediatric patients is provided. Expand
Emergence Delirium in Pediatric Anesthesia
TLDR
The factors that may predict ED are summarized and an intervention algorithm to guide effective prevention and treatment is provided. Expand
Navigating Between Scylla and Charybdis; Sevoflurane for Difficult Sedation at the PICU.
  • J. D. de Graaff, R. Houmes, D. Tibboel
  • Medicine
  • Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
  • 2018
TLDR
The use of an inhalation anesthetic sevoflurane in 23 patients admitted during a 6-year period to two Spanish PICUs when the achievement of an optimal sedation level was difficult with their conventional sedation strategy is presented. Expand
Prevent emergence delirium in paediatric patients undergoing anaesthesia by using propofol or adding an adjuvant to sevoflurane
TLDR
The addition of an adjuvant such as ketamine, dexmedetomidine and opioids as premedication or as part of anaesthesia should be considered to prevent sevoflurane-induced ED. Expand
Effect of xenon and dexmedetomidine as adjuncts for general anesthesia on postoperative emergence delirium after elective cardiac catheterization in children: study protocol for a randomized, controlled, pilot trial
TLDR
The purpose of this study is to estimate the effect size for xenon-dexmedetomidine versus sevoflurane anesthesia with respect to the incidence of emergence delirium in children and to deliver important data required for future prospective clinical trials. Expand
Comparison of maintenance, emergence and recovery characteristics of sevoflurane and desflurane in pediatric ambulatory surgery
TLDR
Desflurane provides faster emergence and recovery in comparison to sevoflurane when used for the maintenance of anesthesia through SGA in children, and can be safely used in children for lower abdominal surgeries. Expand
Dexmedetomidine for the prevention of emergence delirium and postoperative behavioral changes in pediatric patients with sevoflurane anesthesia: a double-blind, randomized trial
TLDR
Dexmedetomidine 0.5 μg/kg reduced the incidence of ED after sevoflurane anesthesia and might be used to prevent NPOBCs and observe postoperative behavioral changes through long-term follow-up. Expand
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