Effects of several virucidal agents on inactivation of influenza, Newcastle disease, and avian infectious bronchitis viruses in the allantoic fluid of chicken eggs.
@article{Abe2007EffectsOS, title={Effects of several virucidal agents on inactivation of influenza, Newcastle disease, and avian infectious bronchitis viruses in the allantoic fluid of chicken eggs.}, author={Motoharu Abe and Kumi Kaneko and Ai Ueda and Hiroshi Otsuka and Kouichi Shiosaki and Chikateru Nozaki and Shuro Goto}, journal={Japanese journal of infectious diseases}, year={2007}, volume={60 6}, pages={ 342-6 } }
General theories on the inactivation of viruses in the presence of a concentrated protein, such as the allantoic fluid of chicken eggs, are not useful. That is, although sodium hypochlorite and sodium hydroxide are generally known as strong virucidal agents, they do not sufficiently inactivate viruses in allantoic fluid. We found that benzalkonium chloride (BC) is an effective virucidal agent against influenza, Newcastle disease, and avian infectious bronchitis viruses even in the presence of a…
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References
SHOWING 1-10 OF 28 REFERENCES
Inactivation of influenza and other viruses by a mixture of virucidal compounds.
- ChemistryApplied microbiology
- 1971
The mixture had no detectable antiviral activity in mice infected with influenza AO/PR/8/34 virus, and this was attributed to the reduced virucidal effect of Resiguard F in the presence of serum proteins.
Isolation and characterization of new infectious bronchitis virus variants in Hungary.
- MedicineActa veterinaria Hungarica
- 1990
Two agents not agglutinating chicken erythrocytes were isolated from organ samples and tracheal swabs taken from 4- to 7-week-old chicks of 8 broiler flocks experiencing respiratory signs and identified as infectious bronchitis virus (IBV) and can be considered distinct variants by cross-neutralization tests.
Inactivation of human viruses by povidone-iodine in comparison with other antiseptics.
- Biology, MedicineDermatology
- 1997
Rubella, measles, mumps viruses and HIV were sensitive to all of the antiseptics, and rotavirus was inactivated by BAC and BEC, while adeno-, polio- and rhinoviruses did not respond to the other antisesptics.
Development of Vero cell-derived inactivated Japanese encephalitis vaccine.
- BiologyBiologicals : journal of the International Association of Biological Standardization
- 2002
The antigen obtained from the manufacturing system was highly purified and its physico-chemical and immunological properties were comparable with those of antigen derived from mouse brains.
From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza
- MedicineNature Reviews Microbiology
- 2004
The transition of reverse-genetic technologies from the research laboratory to the manufacturing environment has presented new challenges for vaccine manufacturers as well as veterinary and public health authorities.
Immunological equivalence between mouse brain-derived and Vero cell-derived Japanese encephalitis vaccines.
- BiologyVirus research
- 2006
Non-clinical and phase I clinical trials of a Vero cell-derived inactivated Japanese encephalitis vaccine.
- Biology, MedicineVaccine
- 2003
Influence of inoculation site of combined oil-adjuvanted vaccine on the antibody response in chickens.
- BiologyThe Journal of veterinary medical science
- 1998
The subcutaneous inoculation into the back of the neck for OILVAX use, and the thigh, lower thigh, breast and shoulder muscle for the possible application of the inoculation outdoors, produced the highest antibody titer, and high antibody titers were observed in the order of lower thigh muscle = thigh muscle > breast muscle > or = shoulder muscle inoculation.
Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children.
- Medicine, BiologyVaccine
- 2002
Japanese Encephalitis Vaccine
- MedicineActa paediatrica Japonica : Overseas edition
- 1988
Since the control of the vector mosquito is hardly to be expected, immunization of man seems t o be the sole available control measure of JE.