Effects of sertraline on autonomic and cognitive functions in healthy volunteers

@article{Siepmann2003EffectsOS,
  title={Effects of sertraline on autonomic and cognitive functions in healthy volunteers},
  author={Martin Siepmann and J Grossmann and Michael M{\"u}ck-Weymann and Wilhelm Kirch},
  journal={Psychopharmacology},
  year={2003},
  volume={168},
  pages={293-298}
}
RationaleThough sertraline, a selective serotonin reuptake inhibitor (SSRI), causes autonomic and cognitive adverse events such as dry mouth and somnolence, there is a paucity of appropriately designed studies on the cognitive and autonomic effects of the drug in the literature.ObjectiveTo compare the effects of sertraline on cognitive and autonomic functions with those of placebo in healthy humans.MethodA randomized, double blind, cross over study of 12 healthy male volunteers aged 24 (21– 32… 
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