Effects of serotonin and the 5-HT2/1C receptor agonist DOI on neurons of the cerebellar dentate/interpositus nuclei: possible involvement of a GABAergic interneuron.

@article{CummingHood1993EffectsOS,
  title={Effects of serotonin and the 5-HT2/1C receptor agonist DOI on neurons of the cerebellar dentate/interpositus nuclei: possible involvement of a GABAergic interneuron.},
  author={P A Cumming-Hood and Howard K. Strahlendorf and Jean C. Strahlendorf},
  journal={European journal of pharmacology},
  year={1993},
  volume={236 3},
  pages={457-65}
}
The present study was designed to examine the effects of iontophoretically applied serotonin (5-HT) on neurons of the cerebellar dentate/interpositus nuclei in an in vitro slice preparation and to determine if the 5-HT2/1C receptor subtype could be responsible for mediating any effects noted with 5-HT. 5-HT and the 5-HT2/1C-selective agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) were iontophoretically applied alone and during superfusion of the 5-HT2/1C-selective… CONTINUE READING