Effects of serotonin-3 receptor antagonists on cytochrome P450 activities in human liver microsomes.

@article{Niwa2006EffectsOS,
  title={Effects of serotonin-3 receptor antagonists on cytochrome P450 activities in human liver microsomes.},
  author={Toshiro Niwa and Sachiko Yamamoto and Miho Saito and Naoto Kobayashi and Kaoru Ikeda and Yasuo Noda and Akira Takagi},
  journal={Biological & pharmaceutical bulletin},
  year={2006},
  volume={29 9},
  pages={1931-5}
}
The effects of three serotonin-3 (5-HT(3)) receptor antagonists, azasetron, ondansetron, and ramosetron, on cytochrome P450 (CYP) 1A2-mediated 7-ethoxyresorufin O-deethylation, CYP2C9-mediated tolbutamide hydroxylation, CYP2C19-mediated S-mephenytoin 4'-hydroxylation, CYP2D6-mediated debrisoquine 4-hydroxylation, CYP2E1-mediated chlorzoxazone 6… CONTINUE READING