Effects of serotonergic compounds on aqueous humor dynamics in monkeys.

@article{Gabelt2001EffectsOS,
  title={Effects of serotonergic compounds on aqueous humor dynamics in monkeys.},
  author={B'ann T Gabelt and Courtney J Millar and Julie A. Kiland and Jennifer A Peterson and Jennifer L Seeman and Paul L. Kaufman},
  journal={Current eye research},
  year={2001},
  volume={23 2},
  pages={120-7}
}
PURPOSE The effects of several serotonergic agonists on aqueous humor formation (AHF), total outflow facility (OF) and intraocular pressure (IOP) were investigated in living cynomolgus monkeys. METHODS We determined the effect of a single topical unilateral 300 microg or 3 mg dose of the 5-HT agonists serotonin, 5-carboxamidotryptamine (5-CT), sumatripan, gepirone, and 8-hydroxy-2(di-n-propylaminotetralin) (8-OH-DPAT) and a 450 microg dose of flesinoxan on IOP (Goldmann applanation tonometry… CONTINUE READING