Effects of selective central muscarinic blockade on schedule-controlled behavior and on the rate-decreasing effects of physostigmine

@article{Hymowitz1984EffectsOS,
  title={Effects of selective central muscarinic blockade on schedule-controlled behavior and on the rate-decreasing effects of physostigmine},
  author={Norman Hymowitz and Henry E. Brezenoff},
  journal={Pharmacology Biochemistry and Behavior},
  year={1984},
  volume={21},
  pages={109-115}
}
View on Elsevier
doi.org
4 Citations
Background Citations
2

4 Citations

Environmental influences on the development of tolerance to the effects of physostigmine on schedule-controlled behavior
TLDR
Tolerance to physostigmine's effects on schedule-controlled behavior is strongly influenced by response requirement, independent of physostIGmine-induced reinforcement loss, and is retained for a substantial period of time in the absence of continued physstigmine administration.
Effects of repeated administration of soman on schedule-controlled behavior and brain in the rat.
Effects of physostigmine and scopolamine on rats' performances in object-recognition and radial-maze tests
TLDR
The results show that in conditions, object recognition is less sensitive than radial-maze test to cholinergic drugs.
Behavioral pharmacology and timing
  • A. Odum
  • Psychology, Biology
    Behavioural Processes
  • 2002

References

SHOWING 1-10 OF 18 REFERENCES
A comparison of antagonists of physostigmine-induced suppression of behavior.
  • G. Vaillant
  • Psychology, Biology
    The Journal of pharmacology and experimental therapeutics
  • 1967
TLDR
Previous observations that physostigmine exerted a very nonspecific suppressant effect upon operant behavior were confirmed and the observed effects seemed mediated by a muscarine-like effect of physstigmine on the central nervous system.
Effects of phencyclidine, atropine and physostigmine, alone and in combination, on variable-interval performance in the squirrel monkey
An unusual type of sympathetic ganglionic stimulant.
  • A. Roszkowski
  • Biology, Medicine
    The Journal of pharmacology and experimental therapeutics
  • 1961
TLDR
It was concluded that sympathetic ganglionic stimulation was responsible for the observed pressor responses, since the pressor activity of McN-A-343 was abolished by bilateral sympathectomy and adrenalectomy.
Rate-dependent effects of drugs: A review of the literature
The modification of drug effects on behavior by external discriminative stimuli.
  • V. Laties
  • Psychology
    The Journal of pharmacology and experimental therapeutics
  • 1972
TLDR
When a discriminative stimulus was not present, chlorpromazine, promazine, d -amphetamine and scopolamine led to pronounced increases in premature switching to the reinforcement key, while Haloperidol had less effect on these performances even though it, like the other drugs, could produce dose-related decreases in rate measures.
A new probe for heterogeneity in muscarinic receptors: 2-methyl-spiro-(1, 3-dioxolane-4, 3')-quinuclidine.
Influence of drugs on behavior controlled by internal and external stimuli.
  • V. Laties, B. Weiss
  • Psychology, Biology
    The Journal of pharmacology and experimental therapeutics
  • 1966
TLDR
Three pigeons were trained to peck an illuminated disk for a food reinforcer which was delivered according to a fixed interval (FI) schedule of reinforcement, confirming the hypothesis that behavior largely controlled by externally based discriminative stimuli is more resistant to drugs than behavior controlled by internal stimuli.
Cardiovascular control by cholinergic mechanisms in the central nervous system.
TLDR
The function of catecholaminergic pathways in the central connections of the autonomic nervous system and the development of drugs which lower blood pressure through stimulation of central adrenergic sites have fostered precocious ad­ vances involving the biogenic amines.
Synthesis and pharmacology of N-(4-diethylamino-2-butynyl)-succinimide (DKJ 21), a new central anticholinergic agent.
A REVISED METHOD FOR THE DETERMINATION OF TOTAL CHOLESTEROL IN BLOOD.
...
...