Effects of selective and non-selective cyclo-oxygenase inhibition on endothelial function in patients with rheumatoid arthritis.

@article{Wong2007EffectsOS,
  title={Effects of selective and non-selective cyclo-oxygenase inhibition on endothelial function in patients with rheumatoid arthritis.},
  author={Min Minnie Wong and Ben Yu Jiang and Karen L McNeill and Stephen Farish and Bruce Kirkham and Phil Chowienczyk},
  journal={Scandinavian journal of rheumatology},
  year={2007},
  volume={36 4},
  pages={265-9}
}
OBJECTIVES Rheumatoid arthritis (RA) is associated with increased cardiovascular disease (CVD) risk that has been attributed to endothelial dysfunction and inflammation. Non-steroidal anti-inflammatory drugs (NSAIDs) and cyclo-oxygenase (COX)-2 inhibitors have been shown in some studies to improve endothelial function in subjects without RA. The aim of this study was to investigate the effects of COX inhibition on endothelial function in patients with RA. METHODS Patients with RA (n = 37… CONTINUE READING