Effects of seasonal variation on the central nervous system activity of Ocimum gratissimum L. essential oil.

@article{Freire2006EffectsOS,
  title={Effects of seasonal variation on the central nervous system activity of Ocimum gratissimum L. essential oil.},
  author={Cristiana Maria Murbach Freire and M{\'a}rcia Ortiz Mayo Marques and Mirtes Costa},
  journal={Journal of ethnopharmacology},
  year={2006},
  volume={105 1-2},
  pages={161-6}
}
Ocimum gratissimum L. (Lamiaceae) and other species of the same genus are used as medicines to treat central nervous system (CNS) diseases, commonly encountered in warm regions of the world. The chemical composition of Ocimum gratissimum essential oil varies according to their chemotypes: timol, eugenol or geraniol. In this study, the essential oil type eugenol was extracted by hydrodistillation in each of the four seasons of the year. Activity upon CNS was evaluated in the open-field and rota… CONTINUE READING
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