Effects of scaling and root planing and subantimicrobial dose doxycycline on gingival crevicular fluid levels of matrix metalloproteinase-8, -13 and serum levels of HsCRP in patients with chronic periodontitis.

@article{Tter2010EffectsOS,
  title={Effects of scaling and root planing and subantimicrobial dose doxycycline on gingival crevicular fluid levels of matrix metalloproteinase-8, -13 and serum levels of HsCRP in patients with chronic periodontitis.},
  author={G{\"u}lay T{\"u}ter and Muhittin Abd{\"u}lkadir Serdar and B{\"u}lent Kurtiş and Stephen G. Walker and Ayşeg{\"u}l Atak and Utku Toyman and Selin Pinar and Tuba Aykan},
  journal={Journal of periodontology},
  year={2010},
  volume={81 8},
  pages={1132-9}
}
BACKGROUND This study evaluates the efficacy of subantimicrobial dose doxycycline (SDD) in conjunction with scaling and root planing (SRP) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (MMP)-8 and -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) in patients with chronic periodontitis (CP). METHODS A total of 41 patients with CP and 17 healthy individuals were included in this randomized controlled trial. CP patients were randomly distributed into… CONTINUE READING

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