Effects of sample processing and storage on the integrity of cell-free miRNAs in maternal plasma.


BACKGROUND Cell-free fetal miRNAs have been identified as potential biomarkers for fetal abnormalities and/or placental function. Factors affecting the stability of cell-free fetal miRNA samples (type of collection tube and time interval between sampling and analysis) have not previously been reported. METHODS Blood from pregnant women (n = 12, 18 ± 4… (More)
DOI: 10.1002/pd.5075