Effects of running exercise on the mandible and tibia of ovariectomized rats

@article{Sakakura2001EffectsOR,
  title={Effects of running exercise on the mandible and tibia of ovariectomized rats},
  author={Yasunori Sakakura and Noriyuki Shide and Eichi Tsuruga and Kazuharu Irie and Toshihiko Yajima},
  journal={Journal of Bone and Mineral Metabolism},
  year={2001},
  volume={19},
  pages={159-167}
}
To examine the effects of running exercise on the mandible and tibia of ovariectomized (OVX) rats, 26-week-old sham-operated (Sham) and OVX rats 1 week post-ovariectomy were subjected to non-exercise (Sham-Cont and OVX-Cont) and exercise (Sham-Exc and OVX-Exc) for 8 weeks. OVX induced a significant decrease in alkaline phosphatase (ALP) and an increase in tartrate-resistant acid phosphatase (TRAP) activity and a reduction of 17β-estradiol in the serum. In OVX-Cont rats, histology and bone… CONTINUE READING