Effects of risedronate on bone marrow adipocytes in postmenopausal women

@article{Duque2010EffectsOR,
  title={Effects of risedronate on bone marrow adipocytes in postmenopausal women},
  author={Gustavo Duque and Wan-qing Li and Meredith Adams and San-zhong Xu and Roger J. Phipps},
  journal={Osteoporosis International},
  year={2010},
  volume={22},
  pages={1547-1553}
}
  • Gustavo Duque, Wan-qing Li, +2 authors Roger J. Phipps
  • Published 2010
  • Medicine
  • Osteoporosis International
  • SummaryAminobisphosphonates promote osteoblastogenesis while inhibiting adipogenesis in vitro. Their effect on adipogenesis in vivo remains unknown. In this study, we demonstrate that risedronate prevents marrow fat infiltration in postmenopausal women after 3 years of treatment.IntroductionAge-related bone loss is associated with high levels of adipogenesis within the bone marrow at the expense of osteoblast population. Bisphosphonates stimulate osteoblastogenesis while inhibiting adipogenesis… CONTINUE READING

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